In 2003, Annika Sorenstam became the first woman to play for 58 years in a men's PGA Tour event
Men and women compete for one trophy at a new event to be organized next year by Swedish golfers Henrik Stenson and Annika Sorenstam.
The Scandinavian Mixed is co-sanctioned by the European Tour and Ladies European Tour and will have 78 men and 78 women in the field.
The event, with a total prize pool of 1.5 million euros (£ 1.3 million), will count towards the world ranking.
It will take place from June 11-14 at Bro Hof Slott in Stockholm.
In addition to counting to world rankings, Race to Dubai points and Ryder Cup points will be available for men and Order of Merit points will be offered for women.
"I am delighted to welcome the Scandinavian Mixed alongside Henrik in Sweden for the next three years," said Sorenstam, who withdrew from competitive golf in 2008 after winning 10 majors.
"Bringing women and men together in a combined tournament is exciting for fans in Sweden and for the global game, because we continue to present golf is a game for everyone."
Women compete against men at the GolfSixes team event, while women's tournaments are held simultaneously with men's events at the Trophee Hassan in Morocco and the Vic Open in Australia, but this is the first time they have fully competed against each other field format.
Stenson, 42, the 2016 Open champion and five-time Ryder Cup player, has committed to play the event for the first three years, while Sorenstam, 49, will play in the pro-ams tournament.