Ranked 304th in the world, the 27-year-old German almost gave up the game because he had neither had won the LPGA Tour or Ladies European Tour. She sobbed with happiness as she held the trophy in the air at the Royal Troon Golf Club in Troon, Scotland.
In addition to the emotional win, Popov took home a check for $ 675,000 winners after shooting three below par 68.
"There has been a lot of fighting over the past six years and I was just glad to overcome it," she said after her victory. "I almost stopped playing last year, thank god I didn't."
Popov led the way into the final day and kept her courage to hold off her nearest match at Jasmine Suwannapura and Minjee Lee.
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In addition to participating in a pandemic, this week's golfers in Scotland were put to the test with three consecutive days of storms.
However, circumstances were settled when the German sunk her last well.
"I used to be the player who didn't like to take the lead and figure out a few positions," said Popov, gifting a friend at a recent LPGA Tour event.
"Inside I felt like I deserved so many good shots over the past three days and I was convinced as I went into this round that whatever happened today, I was always able to get ma king birdies. Kudos to my friend for keeping me calm. "